The ω-3 polyunsaturated fatty acids prevented colitis-associated carcinogenesis through blocking dissociation of β-catenin complex, inhibiting COX-2 through repressing NF-κB, and inducing 15-prostaglandin dehydrogenase

Numerous studies have demonstrated that diets containing an increased ratio of ω-6 : ω-3 polyunsaturated fatty acids (PUFAs) are a risk factor for colon cancer and might affect tumorigenesis. Therefore, dietary ω-3 PUFA administration may be a preventive strategy against colon cancer. Until now, the...

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Publicado en:Oncotarget
Autores principales: Han, Young-Min, Jeong, Migyeung, Park, Jong-Min, Kim, Mi-Young, Go, Eun-Jin, Cha, Ji Young, Kim, Kyung Jo, Hahm, Ki Baik
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325387/
https://ncbi.nlm.nih.gov/pubmed/27566583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11544
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