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Differential effects of prostaglandin derived from ω-6 and ω-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion

Omega-6 (ω-6) polyunsaturated fatty acids (PUFA), abundant in the Western diet, are precursors for a number of key mediators of inflammation including the 2-series of prostaglandins (PG). PGE(2), a cyclooxygenase (COX) metabolite of arachidonic acid, a ω-6 PUFA, is a potent mediator of inflammation...

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Main Authors: Bagga, Dilprit, Wang, Ling, Farias-Eisner, Robin, Glaspy, John A., Reddy, Srinivasa T.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC149905/
https://ncbi.nlm.nih.gov/pubmed/12578976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0334211100
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