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Inhibition of Non-flux-Controlling Enzymes Deters Cancer Glycolysis by Accumulation of Regulatory Metabolites of Controlling Steps

Glycolysis provides precursors for the synthesis of macromolecules and may contribute to the ATP supply required for the constant and accelerated cellular duplication in cancer cells. In consequence, inhibition of glycolysis has been reiteratively considered as an anti-cancer therapeutic option. In...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Physiol
Prif Awduron: Marín-Hernández, Álvaro, Rodríguez-Zavala, José S., Del Mazo-Monsalvo, Isis, Rodríguez-Enríquez, Sara, Moreno-Sánchez, Rafael, Saavedra, Emma
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033973/
https://ncbi.nlm.nih.gov/pubmed/27721794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00412
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