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Control of Metabolite Flux during the Final Steps of Heme b Biosynthesis in Gram-Positive Bacteria

The pathway for assembling heme ends with a unique set of enzymes in Gram-positive bacteria. Substrates for these reactions include coproporphyrin III, Fe(II), and H(2)O(2), which are highly reactive and toxic. Because these bacteria lack membranous compartments, we hypothesized that metabolite flux...

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Publicado en:Biochemistry
Autores principales: Celis, Arianna I., Choby, Jacob E., Kentro, James, Skaar, Eric P., DuBois, Jennifer L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160669/
https://ncbi.nlm.nih.gov/pubmed/31241911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00140
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