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B cells from African American lupus patients exhibit an activated phenotype

Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease driven by both innate and adaptive immune cells. African Americans tend to present with more severe disease at an earlier age compared with patients of European ancestry. In order to better understand the immunological diffe...

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Pubblicato in:JCI Insight
Autori principali: Menard, Laurence C., Habte, Sium, Gonsiorek, Waldemar, Lee, Deborah, Banas, Dana, Holloway, Deborah A., Manjarrez-Orduno, Nataly, Cunningham, Mark, Stetsko, Dawn, Casano, Francesca, Kansal, Selena, Davis, Patricia M., Carman, Julie, Zhang, Clarence K., Abidi, Ferva, Furie, Richard, Nadler, Steven G., Suchard, Suzanne J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033941/
https://ncbi.nlm.nih.gov/pubmed/27699274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87310
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