Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22

Immune-suppressed organ transplant recipients (OTRs) can develop catastrophic squamous cell carcinoma (SCC), characterized by multiple primary tumors, extensive body surface area involvement, or metastases. There are currently no curative systemic therapies available. We previously showed that IL-22...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Abikhair, Melody, Mitsui, Hiroshi, Yanofsky, Valerie, Roudiani, Nazanin, Ovits, Channa, Bryan, Teddy, Oberyszyn, Tatiana M., Tober, Kathleen L., Gonzalez, Juana, Krueger, James G., Felsen, Diane, Carucci, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033893/
https://ncbi.nlm.nih.gov/pubmed/27699266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86434
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