Ruxolitinib inhibits cyclosporine-induced proliferation of cutaneous squamous cell carcinoma

Organ transplant recipients (OTRs) on cyclosporine A (CSA) are prone to catastrophic cutaneous squamous cell carcinoma (SCC). Allograft-sparing, cancer-targeting systemic treatments are unavailable. We have shown increased risk for catastrophic SCC in OTRs via CSA-mediated induction of IL-22. Herein...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Abikhair Burgo, Melody, Roudiani, Nazanin, Chen, Jie, Santana, Alexis L., Doudican, Nicole, Proby, Charlotte, Felsen, Diane, Carucci, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171807/
https://ncbi.nlm.nih.gov/pubmed/30185657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120750
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky