Increased Tc22 and Treg/CD8 Ratio Contribute to Aggressive Growth of Transplant Associated Squamous Cell Carcinoma

Immune suppressed organ transplant recipients suffer increased morbidity and mortality from primary cutaneous SCC. We studied tumor microenvironment in transplant-associated SCC (TSCC), immune-competent SCC and normal skin by IHC, IF and RT-PCR on surgical discard. We determined T cell polarization...

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Detalles Bibliográficos
Main Authors: Zhang, Shali, Fujita, Hideki, Mitsui, Hiroshi, Yanofsky, Valerie R., Fuentes-Duculan, Judilyn, Pettersen, Julia S., Suárez-Fariñas, Mayte, Gonzalez, Juana, Wang, Claire Q. F., Krueger, James G., Felsen, Diane, Carucci, John A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646982/
https://ncbi.nlm.nih.gov/pubmed/23667456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062154
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