Deep sequencing reveals microRNAs predictive of antiangiogenic drug response

The majority of metastatic renal cell carcinoma (RCC) patients are treated with tyrosine kinase inhibitors (TKI) in first-line treatment; however, a fraction are refractory to these antiangiogenic drugs. MicroRNAs (miRNAs) are regulatory molecules proven to be accurate biomarkers in cancer. Here, we...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: García-Donas, Jesús, Beuselinck, Benoit, Inglada-Pérez, Lucía, Graña, Osvaldo, Schöffski, Patrick, Wozniak, Agnieszka, Bechter, Oliver, Apellániz-Ruiz, Maria, Leandro-García, Luis Javier, Esteban, Emilio, Castellano, Daniel E., González del Alba, Aranzazu, Climent, Miguel Angel, Hernando, Susana, Arranz, José Angel, Morente, Manuel, Pisano, David G., Robledo, Mercedes, Rodriguez-Antona, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033860/
https://ncbi.nlm.nih.gov/pubmed/27699216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86051
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