Elimination of p19(ARF)-expressing cells enhances pulmonary function in mice

Senescent cells accumulate in many tissues as animals age and are considered to underlie several aging-associated pathologies. The tumor suppressors p19(ARF) and p16(INK4a), both of which are encoded in the CDKN2A locus, play critical roles in inducing and maintaining permanent cell cycle arrest dur...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Hashimoto, Michihiro, Asai, Azusa, Kawagishi, Hiroyuki, Mikawa, Ryuta, Iwashita, Yuji, Kanayama, Kazuki, Sugimoto, Kazushi, Sato, Tadashi, Maruyama, Mitsuo, Sugimoto, Masataka
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033852/
https://ncbi.nlm.nih.gov/pubmed/27699227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87732
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