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Elimination of p19(ARF)‐expressing cells protects against pulmonary emphysema in mice

Senescent cells accumulate in tissues during aging and are considered to underlie several aging‐associated phenotypes and diseases. We recently reported that the elimination of p19(ARF)‐expressing senescent cells from lung tissue restored tissue function and gene expression in middle‐aged (12‐month‐...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Mikawa, Ryuta, Suzuki, Yohei, Baskoro, Hario, Kanayama, Kazuki, Sugimoto, Kazushi, Sato, Tadashi, Sugimoto, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156494/
https://ncbi.nlm.nih.gov/pubmed/30058137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12827
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