Multiparametric profiling of non–small-cell lung cancers reveals distinct immunophenotypes

BACKGROUND. Immune checkpoint blockade improves survival in a subset of patients with non–small-cell lung cancer (NSCLC), but robust biomarkers that predict response to PD-1 pathway inhibitors are lacking. Furthermore, our understanding of the diversity of the NSCLC tumor immune microenvironment rem...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Lizotte, Patrick H., Ivanova, Elena V., Awad, Mark M., Jones, Robert E., Keogh, Lauren, Liu, Hongye, Dries, Ruben, Almonte, Christina, Herter-Sprie, Grit S., Santos, Abigail, Feeney, Nora B., Paweletz, Cloud P., Kulkarni, Meghana M., Bass, Adam J., Rustgi, Anil K., Yuan, Guo-Cheng, Kufe, Donald W., Jänne, Pasi A., Hammerman, Peter S., Sholl, Lynette M., Hodi, F. Stephen, Richards, William G., Bueno, Raphael, English, Jessie M., Bittinger, Mark A., Wong, Kwok-Kin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033841/
https://ncbi.nlm.nih.gov/pubmed/27699239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89014
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