Breast Cancer Risk Prediction Using a Clinical Risk Model and Polygenic Risk Score

PURPOSE: Breast cancer risk assessment can inform the use of screening and prevention modalities. We investigated the performance of the Breast Cancer Surveillance Consortium (BCSC) risk model in combination with a polygenic risk score (PRS) comprised of 83 single nucleotide polymorphisms identified...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res Treat
Prif Awduron: Shieh, Yiwey, Hu, Donglei, Ma, Lin, Huntsman, Scott, Gard, Charlotte C., Leung, Jessica W.T., Tice, Jeffrey A., Vachon, Celine M., Cummings, Steven R., Kerlikowske, Karla, Ziv, Elad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033764/
https://ncbi.nlm.nih.gov/pubmed/27565998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3953-2
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