A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women

BACKGROUND: More than 180 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility have been identified; these SNPs can be combined into polygenic risk scores (PRS) to predict breast cancer risk. Because most SNPs were identified in predominantly European populations, litt...

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Publicado en:J Natl Cancer Inst
Autores principales: Shieh, Yiwey, Fejerman, Laura, Lott, Paul C, Marker, Katie, Sawyer, Sarah D, Hu, Donglei, Huntsman, Scott, Torres, Javier, Echeverry, Magdalena, Bohórquez, Mabel E, Martínez-Chéquer, Juan Carlos, Polanco-Echeverry, Guadalupe, Estrada-Flórez, Ana P, Haiman, Christopher A, John, Esther M, Kushi, Lawrence H, Torres-Mejía, Gabriela, Vidaurre, Tatianna, Weitzel, Jeffrey N, Zambrano, Sandro Casavilca, Carvajal-Carmona, Luis G, Ziv, Elad, Neuhausen, Susan L
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301155/
https://ncbi.nlm.nih.gov/pubmed/31553449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djz174
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