Breast Cancer Risk Prediction Using a Clinical Risk Model and Polygenic Risk Score

PURPOSE: Breast cancer risk assessment can inform the use of screening and prevention modalities. We investigated the performance of the Breast Cancer Surveillance Consortium (BCSC) risk model in combination with a polygenic risk score (PRS) comprised of 83 single nucleotide polymorphisms identified...

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Udgivet i:Breast Cancer Res Treat
Main Authors: Shieh, Yiwey, Hu, Donglei, Ma, Lin, Huntsman, Scott, Gard, Charlotte C., Leung, Jessica W.T., Tice, Jeffrey A., Vachon, Celine M., Cummings, Steven R., Kerlikowske, Karla, Ziv, Elad
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033764/
https://ncbi.nlm.nih.gov/pubmed/27565998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3953-2
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