Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications

Diabetes is associated with altered cellular metabolism, but how altered metabolism contributes to the development of diabetic complications is unknown. We used the BKS db/db diabetic mouse model to investigate changes in carbohydrate and lipid metabolism in kidney cortex, peripheral nerve, and reti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Sas, Kelli M., Kayampilly, Pradeep, Byun, Jaeman, Nair, Viji, Hinder, Lucy M., Hur, Junguk, Zhang, Hongyu, Lin, Chengmao, Qi, Nathan R., Michailidis, George, Groop, Per-Henrik, Nelson, Robert G., Darshi, Manjula, Sharma, Kumar, Schelling, Jeffrey R., Sedor, John R., Pop-Busui, Rodica, Weinberg, Joel M., Soleimanpour, Scott A., Abcouwer, Steven F., Gardner, Thomas W., Burant, Charles F., Feldman, Eva L., Kretzler, Matthias, Brosius, Frank C., Pennathur, Subramaniam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033761/
https://ncbi.nlm.nih.gov/pubmed/27699244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86976
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