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Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease

Both type 1 and type 2 diabetes are associated with altered lipid metabolism, which might in part contribute to debilitating complications such as diabetic kidney disease (DKD). Ceramides are bioactive sphingolipids that have been implicated in a variety of diseases as they can regulate cellular res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Proteomics Bioinform
Hauptverfasser: Sas, Kelli M, Nair, Viji, Byun, Jaeman, Kayampilly, Pradeep, Zhang, Hongyu, Saha, Jharna, Brosius, Frank C, Kretzler, Matthias, Pennathur, Subramaniam
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712744/
https://ncbi.nlm.nih.gov/pubmed/26778897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/jpb.S14-002
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