Tissue-specific metabolic reprogramming drives nutrient flux in diabetic complications

Diabetes is associated with altered cellular metabolism, but how altered metabolism contributes to the development of diabetic complications is unknown. We used the BKS db/db diabetic mouse model to investigate changes in carbohydrate and lipid metabolism in kidney cortex, peripheral nerve, and reti...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sas, Kelli M., Kayampilly, Pradeep, Byun, Jaeman, Nair, Viji, Hinder, Lucy M., Hur, Junguk, Zhang, Hongyu, Lin, Chengmao, Qi, Nathan R., Michailidis, George, Groop, Per-Henrik, Nelson, Robert G., Darshi, Manjula, Sharma, Kumar, Schelling, Jeffrey R., Sedor, John R., Pop-Busui, Rodica, Weinberg, Joel M., Soleimanpour, Scott A., Abcouwer, Steven F., Gardner, Thomas W., Burant, Charles F., Feldman, Eva L., Kretzler, Matthias, Brosius, Frank C., Pennathur, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033761/
https://ncbi.nlm.nih.gov/pubmed/27699244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86976
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC5033761/
https://ncbi.nlm.nih.gov/pubmed/27699244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86976

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