MUTYH promotes oxidative microglial activation and inherited retinal degeneration

Oxidative stress is implicated in various neurodegenerative disorders, including retinitis pigmentosa (RP), an inherited disease that causes blindness. The biological and cellular mechanisms by which oxidative stress mediates neuronal cell death are largely unknown. In a mouse model of RP (rd10 mice...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Nakatake, Shunji, Murakami, Yusuke, Ikeda, Yasuhiro, Morioka, Noriko, Tachibana, Takashi, Fujiwara, Kohta, Yoshida, Noriko, Notomi, Shoji, Hisatomi, Toshio, Yoshida, Shigeo, Ishibashi, Tatsuro, Nakabeppu, Yusaku, Sonoda, Koh-Hei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033752/
https://ncbi.nlm.nih.gov/pubmed/27699246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87781
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