MUTYH promotes oxidative microglial activation and inherited retinal degeneration

Oxidative stress is implicated in various neurodegenerative disorders, including retinitis pigmentosa (RP), an inherited disease that causes blindness. The biological and cellular mechanisms by which oxidative stress mediates neuronal cell death are largely unknown. In a mouse model of RP (rd10 mice...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Nakatake, Shunji, Murakami, Yusuke, Ikeda, Yasuhiro, Morioka, Noriko, Tachibana, Takashi, Fujiwara, Kohta, Yoshida, Noriko, Notomi, Shoji, Hisatomi, Toshio, Yoshida, Shigeo, Ishibashi, Tatsuro, Nakabeppu, Yusaku, Sonoda, Koh-Hei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033752/
https://ncbi.nlm.nih.gov/pubmed/27699246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87781
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