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Functional Impact of Ryanodine Receptor Oxidation on Intracellular Calcium Regulation in the Heart
Type 2 ryanodine receptor (RyR2) serves as the major intracellular Ca(2+) release channel that drives heart contraction. RyR2 is activated by cytosolic Ca(2+) via the process of Ca(2+)-induced Ca(2+) release (CICR). To ensure stability of Ca(2+) dynamics, the self-reinforcing CICR must be tightly co...
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| Publicado no: | Rev Physiol Biochem Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033687/ https://ncbi.nlm.nih.gov/pubmed/27251471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/112_2016_2 |
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