Nalaganje...
A Novel Inhibitor of 5-Lipoxygenase (5-LOX) Prevents Oxidative Stress–Induced Cell Death of Retinal Pigment Epithelium (RPE) Cells
PURPOSE: 5-Lipoxygenase (5-LOX) oxygenates arachidonic acid to form 5-hydroperoxyeicosatetraenoic acid, which is further converted into biologically detrimental leukotrienes, such as leukotriene B4 (LTB(4)). The RPE and retina express the PNPLA2 gene for pigment epithelium–derived factor receptor (P...
Shranjeno v:
| izdano v: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Association for Research in Vision and Ophthalmology
2016
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033602/ https://ncbi.nlm.nih.gov/pubmed/27635633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-19039 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|