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Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases

Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...

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Publicat a:PLoS One
Autors principals: Kanwal, Rajnee, Datt, Manish, Liu, Xiaoqi, Gupta, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033486/
https://ncbi.nlm.nih.gov/pubmed/27658199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162956
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