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DNA Methyltransferase and Histone Deacetylase Inhibitors in the Treatment of Myelodysplastic Syndromes
The recently approved drugs 5-azacitidine and 5-aza-2′-deoxyazacytidine are in wide clinical use for the treatment of myelodysplastic syndrome of all types and chronic myelomonocytic leukemia. These agents were developed based upon an understanding of the importance of epigenetic changes in malignan...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234265/ https://ncbi.nlm.nih.gov/pubmed/18179966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2007.11.007 |
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