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Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases

Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kanwal, Rajnee, Datt, Manish, Liu, Xiaoqi, Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033486/
https://ncbi.nlm.nih.gov/pubmed/27658199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162956
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