G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation

Fermentation of dietary fibre in the gut yields large amounts of short chain fatty acids (SCFAs). SCFAs can impart biological responses in cells through their engagement of ‘metabolite-sensing’ G protein-coupled receptors (GPCRs). One of the main SCFA receptors, GPR43, is highly expressed by neutrop...

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Publicat a:PLoS One
Autors principals: Kamp, Marjon E., Shim, Raymond, Nicholls, Alyce J., Oliveira, Ana Carolina, Mason, Linda J., Binge, Lauren, Mackay, Charles R., Wong, Connie H. Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033414/
https://ncbi.nlm.nih.gov/pubmed/27658303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163750
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