Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability

Frontotemporal dementia (FTD) and other tauopathies characterized by focal brain neurodegeneration and pathological accumulation of proteins are commonly associated with tau mutations. However, the mechanism of neuronal loss is not fully understood. To identify molecular events associated with tauop...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Reports
Asıl Yazarlar: Silva, M. Catarina, Cheng, Chialin, Mair, Waltraud, Almeida, Sandra, Fong, Helen, Biswas, M. Helal U., Zhang, Zhijun, Huang, Yadong, Temple, Sally, Coppola, Giovanni, Geschwind, Daniel H., Karydas, Anna, Miller, Bruce L., Kosik, Kenneth S., Gao, Fen-Biao, Steen, Judith A., Haggarty, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032560/
https://ncbi.nlm.nih.gov/pubmed/27594585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.001
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