Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability

Frontotemporal dementia (FTD) and other tauopathies characterized by focal brain neurodegeneration and pathological accumulation of proteins are commonly associated with tau mutations. However, the mechanism of neuronal loss is not fully understood. To identify molecular events associated with tauop...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Silva, M. Catarina, Cheng, Chialin, Mair, Waltraud, Almeida, Sandra, Fong, Helen, Biswas, M. Helal U., Zhang, Zhijun, Huang, Yadong, Temple, Sally, Coppola, Giovanni, Geschwind, Daniel H., Karydas, Anna, Miller, Bruce L., Kosik, Kenneth S., Gao, Fen-Biao, Steen, Judith A., Haggarty, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032560/
https://ncbi.nlm.nih.gov/pubmed/27594585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.001
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items