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Comparative Neurotoxicity Screening in Human iPSC-derived Neural Stem Cells, Neurons and Astrocytes

Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique source of human primary cells for toxicity screens. Here, we report on the comparative cytotoxicity of 80 compounds (neurotoxicants, developmental neurotoxicants, environmental compounds) in iPSC as well as iso...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Pei, Ying, Peng, Jun, Behl, Mamta, Sipes, Nisha S, Shockley, Keith R, Rao, Mahendra S, Tice, Raymond R, Zeng, Xianmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032144/
https://ncbi.nlm.nih.gov/pubmed/26254731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.07.048
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