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Induction of MAP kinase phosphatase 3 through Erk/MAP kinase activation in three oncogenic Ras (H-, K- and N-Ras)-expressing NIH/3T3 mouse embryonic fibroblast cell lines

Ras oncoproteins are small molecular weight GTPases known for their involvement in oncogenesis, which operate in a complex signaling network with multiple effectors. Approximately 25% of human tumors possess mutations in a member of this family. The Raf1/MEK/Erk1/2 pathway is one of the most intensi...

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Vydáno v:BMB Rep
Hlavní autoři: Koo, JaeHyung, Wang, Sen, Kang, NaNa, Hur, Sun Jin, Bahk, Young Yil
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032004/
https://ncbi.nlm.nih.gov/pubmed/26818088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2016.49.7.256
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