Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis

AIMS: Invaginations of the cellular membrane called t-tubules are essential for maintaining efficient excitation–contraction coupling in ventricular cardiomyocytes. Disruption of t-tubule structure during heart failure has been linked to dyssynchronous, slowed Ca(2+) release and reduced power of the...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Frisk, Michael, Ruud, Marianne, Espe, Emil K. S., Aronsen, Jan Magnus, Røe, Åsmund T., Zhang, Lili, Norseng, Per Andreas, Sejersted, Ole M., Christensen, Geir A., Sjaastad, Ivar, Louch, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031949/
https://ncbi.nlm.nih.gov/pubmed/27226008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw111
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