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Accounting for selection and correlation in the analysis of two-stage genome-wide association studies

The problem of selection bias has long been recognized in the analysis of two-stage trials, where promising candidates are selected in stage 1 for confirmatory analysis in stage 2. To efficiently correct for bias, uniformly minimum variance conditionally unbiased estimators (UMVCUEs) have been propo...

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Bibliografische gegevens
Gepubliceerd in:Biostatistics
Hoofdauteurs: Robertson, David S., Prevost, A. Toby, Bowden, Jack
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031943/
https://ncbi.nlm.nih.gov/pubmed/26993061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxw012
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