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Accounting for selection and correlation in the analysis of two-stage genome-wide association studies
The problem of selection bias has long been recognized in the analysis of two-stage trials, where promising candidates are selected in stage 1 for confirmatory analysis in stage 2. To efficiently correct for bias, uniformly minimum variance conditionally unbiased estimators (UMVCUEs) have been propo...
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| Veröffentlicht in: | Biostatistics |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031943/ https://ncbi.nlm.nih.gov/pubmed/26993061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxw012 |
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