Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium

BACKGROUND: Exacerbations of asthma and COPD are triggered by rhinoviruses. Uncontrolled inflammatory pathways, pathogenic bacterial burden and impaired antiviral immunity are thought to be important factors in disease severity and duration. Macrolides including azithromycin are often used to treat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Antimicrob Chemother
Hlavní autoři: Porter, James D., Watson, Jennifer, Roberts, Lee R., Gill, Simren K., Groves, Helen, Dhariwal, Jaideep, Almond, Mark H., Wong, Ernie, Walton, Ross P., Jones, Lyn H., Tregoning, John, Kilty, Iain, Johnston, Sebastian L., Edwards, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031920/
https://ncbi.nlm.nih.gov/pubmed/27494903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw222
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky