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Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity

Adaptive immunity is the specialized defence mechanism in vertebrates that evolved to eliminate pathogens. Specialized lymphocytes recognize specific protein epitopes through antigen receptors to mount potent immune responses, many of which are initiated by nuclear factor-kappa B activation and gene...

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Pubblicato in:Philos Trans A Math Phys Eng Sci
Autori principali: Klein, Theo, Viner, Rosa I., Overall, Christopher M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031638/
https://ncbi.nlm.nih.gov/pubmed/27644975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsta.2015.0372
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