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A Platform for Interrogating Cancer-Associated p53 Alleles

p53 is the most frequently mutated gene in human cancer. Compelling evidence argues that full transformation involves loss of growth suppression encoded by wild-type p53 together with poorly understood oncogenic activity encoded by missense mutations. Furthermore, distinguishing disease alleles from...

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Bibliografische gegevens
Gepubliceerd in:Oncogene
Hoofdauteurs: D’Brot, Alejandro, Kurtz, Paula, Regan, Erin, Jakubowski, Brandon, Abrams, John M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031501/
https://ncbi.nlm.nih.gov/pubmed/26996664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.48
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