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A Platform for Interrogating Cancer-Associated p53 Alleles
p53 is the most frequently mutated gene in human cancer. Compelling evidence argues that full transformation involves loss of growth suppression encoded by wild-type p53 together with poorly understood oncogenic activity encoded by missense mutations. Furthermore, distinguishing disease alleles from...
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| Udgivet i: | Oncogene |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031501/ https://ncbi.nlm.nih.gov/pubmed/26996664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.48 |
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