Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons

The Slit protein is a major midline repellent for central nervous system (CNS) axons. In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments, but the biological significance of this is unknown. Analysis in the Drosophila ventral nerve cord of a slit allele (slit-UC) that cannot be...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Alavi, Maryam, Song, Minmin, King, Gracie L. Andrews, Gillis, Taylor, Propst, Robert, Lamanuzzi, Matthew, Bousum, Adam, Miller, Amanda, Allen, Ryan, Kidd, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031454/
https://ncbi.nlm.nih.gov/pubmed/27654876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002560
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