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Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor Commissureless, which reduces surface expressio...
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Publicado no: | eLife |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505356/ https://ncbi.nlm.nih.gov/pubmed/26186094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08407 |
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