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Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons

During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor Commissureless, which reduces surface expressio...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Evans, Timothy A, Santiago, Celine, Arbeille, Elise, Bashaw, Greg J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505356/
https://ncbi.nlm.nih.gov/pubmed/26186094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08407
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