Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

BACKGROUND: Patient derived xenografts (PDX) are generated by transplanting the original patient’s tumor tissue into immune-deficient mice. Unlike xenograft models derived from cell lines, PDX models can better preserve the histopathology from the original patient and molecular pathways. High-grade...

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Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Dong, Ruifen, Qiang, Wenan, Guo, Haiyang, Xu, Xiaofei, Kim, J. Julie, Mazar, Andrew, Kong, Beihua, Wei, Jian-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031262/
https://ncbi.nlm.nih.gov/pubmed/27655386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0318-6
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