Molecular correlates of platinum response in human high‐grade serous ovarian cancer patient‐derived xenografts

INTRODUCTION: Improvement in the ability to target underlying drivers and vulnerabilities of high‐grade serous ovarian cancer (HG‐SOC) requires the development of molecularly annotated pre‐clinical models reflective of clinical responses. METHODS: We generated patient‐derived xenografts (PDXs) from...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Topp, Monique D., Hartley, Lynne, Cook, Michele, Heong, Valerie, Boehm, Emma, McShane, Lauren, Pyman, Jan, McNally, Orla, Ananda, Sumitra, Harrell, Marisol, Etemadmoghadam, Dariush, Galletta, Laura, Alsop, Kathryn, Mitchell, Gillian, Fox, Stephen B., Kerr, Jeffrey B., Hutt, Karla J., Kaufmann, Scott H., Swisher, Elizabeth M., Bowtell, David D., Wakefield, Matthew J., Scott, Clare L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400120/
https://ncbi.nlm.nih.gov/pubmed/24560445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.01.008
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