miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma

High-grade serous ovarian carcinoma (HGSOC), the most common and aggressive subtype of epithelial ovarian cancer, is characterized by TP53 mutations and genetic instability. Using miRNA profiling analysis, we found that miR-145, a p53 regulated miRNA, was frequently down-regulated in HGSOC. miR-145...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dong, Ruifen, Liu, Xiaolin, Zhang, Qing, Jiang, Zhijun, Li, Yingwei, Wei, Yuyan, Li, Yinuo, Yang, Qifeng, Liu, Jinsong, Wei, Jian-Jun, Shao, Changshun, Liu, Zhaojian, Kong, Beihua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279412/
https://ncbi.nlm.nih.gov/pubmed/25333261
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