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P53 and the defenses against genome instability caused by transposons and repetitive elements

The recent publication by Wylie et al. is reviewed, demonstrating that the p53 protein regulates the movement of transposons. While this work presents genetic evidence for a piRNA‐mediated p53 interaction with transposons in Drosophila and zebrafish, it is herein placed in the context of a decade or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioessays
Hauptverfasser: Levine, Arnold J., Ting, David T., Greenbaum, Benjamin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031199/
https://ncbi.nlm.nih.gov/pubmed/27172878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600031
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