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Exaptive origins of regulated mRNA decay in eukaryotes

Eukaryotic gene expression is extensively controlled at the level of mRNA stability and the mechanisms underlying this regulation are markedly different from their archaeal and bacterial counterparts. We propose that two such mechanisms, nonsense‐mediated decay (NMD) and motif‐specific transcript de...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Hamid, Fursham M., Makeyev, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031192/
https://ncbi.nlm.nih.gov/pubmed/27438915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600100
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