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Regulation of mRNA Abundance by Polypyrimidine Tract-Binding Protein-Controlled Alternate 5′ Splice Site Choice

Alternative splicing (AS) provides a potent mechanism for increasing protein diversity and modulating gene expression levels. How alternate splice sites are selected by the splicing machinery and how AS is integrated into gene regulation networks remain important questions of eukaryotic biology. Her...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Hamid, Fursham M., Makeyev, Eugene V.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222953/
https://ncbi.nlm.nih.gov/pubmed/25375251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004771
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