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Absolute quantification of matrix metabolites reveals the dynamics of mitochondrial metabolism

Mitochondria house metabolic pathways that impact most aspects of cellular physiology. While metabolite profiling by mass spectrometry is widely applied at the whole-cell level, it is not routinely possible to measure the concentrations of small molecules in mammalian organelles. We describe a metho...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Chen, Walter W., Freinkman, Elizaveta, Wang, Tim, Birsoy, Kıvanç, Sabatini, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030821/
https://ncbi.nlm.nih.gov/pubmed/27565352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.07.040
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