G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling

Cytokine-induced neutrophil mobilization from the bone marrow to circulation is a critical event in acute inflammation, but how it is accurately controlled remains poorly understood. In this study, we report that CXCR2 ligands are responsible for rapid neutrophil mobilization during early-stage acut...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Bajrami, Besnik, Zhu, Haiyan, Kwak, Hyun-Jeong, Mondal, Subhanjan, Hou, Qingming, Geng, Guangfeng, Karatepe, Kutay, Zhang, Yu C., Nombela-Arrieta, César, Park, Shin-Young, Loison, Fabien, Sakai, Jiro, Xu, Yuanfu, Silberstein, Leslie E., Luo, Hongbo R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030805/
https://ncbi.nlm.nih.gov/pubmed/27551153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160393
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