Myeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis

The cellular mechanisms controlling infection-induced emergency granulopoiesis are poorly defined. Here we found that reactive oxygen species (ROS) concentrations in the bone marrow (BM) were elevated during acute infection in a phagocytic NADPH oxidase-dependent manner in myeloid cells. Gr1(+) myel...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Kwak, Hyun-Jeong, Liu, Peng, Bajrami, Besnik, Xu, Yuanfu, Park, Shin-Young, Nombela-Arrieta, Cesar, Mondal, Subhanjan, Sun, Yan, Zhu, Haiyan, Chai, Li, Silberstein, Leslie E., Cheng, Tao, Luo, Hongbo R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303526/
https://ncbi.nlm.nih.gov/pubmed/25579427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.12.017
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