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Modeling Ca(2+)-Bound Troponin in Excitation Contraction Coupling

To explain disparate decay rates of cytosolic Ca(2+) and structural changes in the thin filaments during a twitch, we model the time course of Ca(2+)-bound troponin (Tn) resulting from the free Ca(2+) transient of fast skeletal muscle. In fibers stretched beyond overlap, the decay of Ca(2+) as measu...

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Publié dans:Front Physiol
Auteurs principaux: Zot, Henry G., Hasbun, Javier E.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030304/
https://ncbi.nlm.nih.gov/pubmed/27708586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00406
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