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Modeling Na(+)-Ca(2+) exchange in the heart: allosteric activation, spatial localization, sparks and excitation-contraction coupling
The cardiac sodium (Na(+))/calcium (Ca(2+)) exchanger (NCX1) is an electrogenic membrane transporter that regulates Ca(2+) homeostasis in cardiomyocytes, serving mainly to extrude Ca(2+) during diastole. The direction of Ca(2+) transport reverses at membrane potentials near that of the action potent...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5534334/ https://ncbi.nlm.nih.gov/pubmed/27377851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.06.068 |
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